Halohydrins are compounds containing a vicinal (adjacent) halogen and a hydroxyl groups. Halohydrins are prepared by the traction of alkenes with halogens in the presence of water: Recall that in neutral solvents such as CCl4 and DCM, the … Read more
Markovnikov’s Rule In the previous post, we talked about the addition reaction of hydrogen halides (HCl, HBr, and HI) to alkenes, and learned about Markovnikov’s rule, which states that in these reactions, the halogen adds to the more substituted carbon … Read more
When 1,2-diols (vicinal diols) are treated with acid, a rearrangement takes place, and the diol is transformed to a ketone. This reaction is known as the pinacol rearrangement since pinacol is the simplest diol capable of undergoing such … Read more
