In the previous post, we learned that the crossed aldol condensation is the aldol reaction between two different carbonyl compounds. This is also known as a mixed aldol reaction. Crossed aldol reactions have the advantage of controlling which carbonyl compound serves … Read more
In the previous post, we discussed the acetoacetic ester synthesis, which is a method for preparing substituted methyl ketones via alkylation of the acetoacetic ester followed by hydrolysis and decarboxylation. Below are some practice problems on the acetoacetic ester synthesis … Read more
In the previous post we discussed the alkylation reactions of enolates, which are one of the most important transformations in carbonyl chemistry. Enolates are typically formed from carbonyl compounds, but they are not limited to aldehydes and ketones. Similar enolate-type … Read more
In the previous post, we talked about the alpha halogenation of aldehydes and ketones and its application in organic synthesis. So, if you have already gone over this material, go ahead and work on these practice problems. The second part … Read more
