When a cyclic diene is used in the Diels-Alder reaction, a bridged bicyclic compound is formed: This looks ordinary until we draw the product from a side view, which reveals some nice structures and interesting features of the … Read more
In this post, we will discuss how to predict the product of Diels–Alder reactions. The key idea is that you are forming two new σ bonds between the diene and the dienophile in a single step, so you need to … Read more
The mechanism of electrophilic addition to dienes is similar to what we learn in the addition reactions of alkenes. The difference here is that there are two double bonds, and the question you may start wondering about is: “Which of … Read more
Why do you think the following Grignard reaction is impossible to carry out without having a protecting group on the alcohol? What is even a protecting group? These are the questions we are going to address in today’s article. … Read more
The main difference of the Grignard reaction compared to everything else you learn in the reactions of alcohols is that it is another way of making a new C-C bond and extending the carbon chain of the molecule. The most … Read more
In this post, we will talk about the Grignard reaction – a fundamental reaction in organic chemistry discovered by Victor Grignard in 1912, which gave him the Nobel prize award. The most common and important Grignard reaction is the one … Read more
Importance of radical Halogenation The source of the large majority of organic materials used for a countless number of applications, which can be plastics, drugs, paints, clothes, electronics and many more is the crude oil. We need to … Read more
The first practice problem is a summary of alkyne reactions, followed by comprehensive synthesis practice problems; all the major classes of alkyne and alkene reactions are covered!These include the preparation of dialkyl halides and their use in the preparation of … Read more
Alkylation of Terminal Alkynes Many reactions of alkynes are similar to those of alkenes, as they are both π-bond systems that are capable of doing electrophilic addition reactions. One important difference is the acidity of the alkyne proton. The pKa … Read more
